This gene encodes coagulation factor VIII, which participates in the intrinsic pathway of blood coagulation; factor VIII is a cofactor for factor IXa which, in the presence of Ca+2 and phospholipids, converts factor X to the activated form Xa. This gene produces two alternatively spliced transcripts. Transcript variant 1 encodes a large glycoprotein, isoform a, which circulates in plasma and associates with von Willebrand factor in a noncovalent complex. This protein undergoes multiple cleavage events. Transcript variant 2 encodes a putative small protein, isoform b, which consists primarily of the phospholipid binding domain of factor ...
Cat # 16393035
100 µL
Cat # 11588872
500 µg
Cat # 11598872
500 µg
Cat # 15774907
0.025 mg
Cat # 16620905
100 µL
Cat # 11518882
500 µg
Cat # 11345433
100 µL
Cat # 16334104
100 µL
Cat # 15737615
0.1 ml
Cat # 11549882
100 µg
Cat # 15294633
500 µg
Cat # 15764907
0.1 mg
Cat # 11598820
1 mg
Cat # 16354104
100 µL
Cat # 15994795
100 µg
Cat # 16344104
100 µL
Cat # 11508882
500 µg
Cat # 16633315
100 µL
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